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Paediatric Treatment - Gastro-Intestinal Tract Infections

Infectious diarrhoea

NICE-CKS

Antibiotic therapy not indicated unless systemically unwell. 2 C. If systemically unwell and Campylobacter spp suspected (e.g. undercooked meat and abdominal pain), consider clarithromycin for 5–7 days if treated early (within 3 days). 3 C
Refer previously healthy children with acute painful or bloody diarrhoea to exclude E. coli 0157 infection. 1 C

Medicine Calendar

If systematically unwell and Campylobacter spp suspected, consider clarithromycin if treated early (within 3 days).3 C

See BNFc

5–7 days

Threadworm

NICE-CKS

Treat all household contacts at the same time PLUS advise hygiene measures for 2 weeks (hand hygiene, pants at night, morning shower [include perianal area]) PLUS wash sleepwear, bed linen, dust, and vacuum on day one. 1 C
Child <6 mths add perianal wet wiping or washes 3 hourly during the day.

Medicine Calendar

All patients over 6 months:
mebendazole (off- label if <2yrs)

100mg 1 C

stat dose but repeat after 2 weeks if infestation persists

Child <6 mths mebendazole is unlicensed, use hygiene measures alone for 6 weeks1 C

The POCAST project is funded by the National Institute for Health Research Health Protection Research Unit (NIHR HPRU) in Healthcare Associated Infections and Antimicrobial Resistance at Imperial College London and by the Imperial College Healthcare Charity (Grant Ref No:7006/P36U).