HPA. The management of scabies in the community. Health Protection Agency North West. 2005. http://www.wirralct.nhs.uk/attachments/article/25/ScabiesInTheCommunity.pdf Accessed 22.09.14. RATIONALE: Treatment of all contacts: expert opinion is that the index case and all members of the household and sexual contacts should be treated within 24 hours of one another, even in the absence of symptoms, to reduce the risk of re-infestation. Two treatments, 7 days apart: expert opinion is that two treatment sessions are needed to treat scabies effectively.

ABPI Medicines Compendium. Lyclear Dermal Cream. Datapharm Communications Ltd. 2008. http://www.medicines.org.uk/EMC/medicine/10439/SPC/Lyclear+Dermal+Cream/ Accessed 23.09.14.

Strong M, Johnstone P. Interventions for treating scabies. Cochrane Database of Systematic Reviews. 2007. Issue 3 http://www.mrw.interscience.wiley.com/cochrane/clsysrev/articles/CD000320/frame.html Accessed 23.09.14. RATIONALE: Permethrin: topical permethrin appeared more effective than oral ivermectin, topical crotamiton, and topical lindane. The greatest body of evidence is for topical permethrin compared with lindane (n = 735, five RCTs: RR 0.32, 95% CI 0.13 to 0.75). Malathion: no RCTs were found that evaluated the efficacy of malathion for the treatment of scabies. Malathion has only been evaluated in uncontrolled studies.

The POCAST project is funded by the National Institute for Health Research Health Protection Research Unit (NIHR HPRU) in Healthcare Associated Infections and Antimicrobial Resistance at Imperial College London and by the Imperial College Healthcare Charity (Grant Ref No:7006/P36U).